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2 week period, significantly better than each risperadone and placebo (Table 2). The number of calories consumed was numerically higher, but didn't reach significance. Response to phenelzine and imipramine in placebo non-responders with atypical depression: a new utility of the crossover design. Bowden CL, Calabrese JR, McElroy SL, Gyulai L, Wassef A, Petty F, Pope HG Jr, Chou JC, Keck PE Jr, Rhodes LJ, Swann AC, Hirschfeld RM, Wozniak PJ.A randomized, placebo-managed 12-month trial of divalproex and lithium in remedy of out patients with bipolar I disorder. Charles C. Bowden in the 1990s demonstrated that valproate semisodium (divalproex) an anticonvulsant, had comparable efficacy to lithium, the standard mood stabilizer, within the treatment of mania and bipolar disorder (Bowden, Brugger, Swann et al. Frederic Quitkin, a disciple of Klein, corroborated within the late 1980s and early 1990s the diagnostic idea of "atypical depression" (Quitkin, McGrath, Stewart et al.